HEALTH / WELL-BEING

576. Accelerated Neurodegeneration: Effects of Cumulative Trauma Exposure and Chronic Posttraumatic Stress Disorder (PTSD) in Relatively Young Combat Veterans

Article

This article examines how combat veterans with PTSD (CV+PTSD) compared to healthy combat veterans (HCV) had significantly reduced gray matter volume (GMV) of olfactory cortex that was inversely related to burning odor sensitivity and considers olfactory GMV and smell identification as a function of age in combat veterans with and without PTSD.

Abstract

We previously published that combat veterans with PTSD (CV+PTSD) compared to healthy combat veterans (HCV) had significantly reduced gray matter volume (GMV) of olfactory cortex that was inversely related to burning odor sensitivity. Given that olfactory deficits (smell identification) are an early symptom of neurodegenerative disorder, and that some consider PTSD a disorder of accelerating aging, we sought to examine olfactory GMV and smell identification as a function of age in combat veterans with and without PTSD.

Full Reference

Coreste, B., Schumann, A., Uhde, T.. 2017. 576. Accelerated Neurodegeneration: Effects of Cumulative Trauma Exposure and Chronic Posttraumatic Stress Disorder (PTSD) in Relatively Young Combat Veterans. Biological Psychiatry. 81:10, S233.