HEALTH / WELL-BEING

Acute effects of normal saline and lactated Ringer’s with erythropoietin on microcirculatory perfusion, tissue bioenergetics, and gut permeability of the small intestine in a hemorrhagic shock and resuscitation rat model

Article

Abstract

Erythropoietin (EPO) has acute hemodynamic and anti-inflammatory effects in addition to its erythropoietic action. We tested the hypothesis that recombinant human EPO (rHuEPO) given at the time of resuscitation with normal saline (NS) or lactated Ringer’s (LR) will improve capillary perfusion and tissue bioenergetics in a hemorrhagic shock and resuscitation (HS/R) rat model.

Full Reference

Acute effects of normal saline and lactated Ringer’s with erythropoietin on microcirculatory perfusion, tissue bioenergetics, and gut permeability of the small intestine in a hemorrhagic shock and resuscitation rat model. Raymond L.C. Kao, Weixiong Huang, Anargyros Xenocostas, David Driman, Claudio M. Martin, Tina Mele, Neil Parry, and Tao Rui 2015 1:1, 68–80.