Opioid Medication Use in Patients with Gastrointestinal Diagnoses vs. Unexplained Gastrointestinal Symptoms in the US Veterans Health Administration


The aim of this study is to compare opioid use among veterans with gastrointestinal diagnoses and those with unexplained gastrointestinal symptoms.


Background While opioid prescriptions have increased alarmingly in the United States (US), their use for unexplained chronic gastrointestinal (GI) pain (eg, irritable bowel syndrome) carries an especially high risk for adverse effects and questionable benefit. Aim To compare opioid use among US veterans with structural GI diagnoses (SGID) and those with unexplained GI symptoms or functional GI diagnoses (FGID), a group for whom opioids have no accepted role.

Full Reference

Sayuk, G. S. ; Kanuri, N. ; Gyawali, C. P. ; Gott, B. M. ; Nix, B. D. ; Rosenheck, R. A. (2018). Opioid medication use in patients with gastrointestinal diagnoses vs unexplained gastrointestinal symptoms in the US Veterans Health Administration. Journal of Alimentary Pharmacology and Therapeutics. Vol: 47 (6), p. 784-91.